43 yo lady complaining of a nodule of the
left parotid gland. The nodule increased in size steadily for the last
4 months. On physical examination the nodule was firm, fixed to the parotid
gland. No other complaint reported, and the rest of the physical exam
A frozen section revealed an atypical lympho-epithelial
lesion. Superficial parotidectomy performed.
Mixture of lymphoid cells, varying
in size, with high mitotic activity.
Intrication of the lymphoid infiltrate
and the epithelial clusters. Higher power on the lymphoid component,
Serologic workout for systemic
diseases was negative
The second area observed on HE, CD3.
Sections from the surrounding
MALT-Lymphoma of the parotid
gland with large B-cell component consistent a higher grade transformation.
Appropriate evaluation of other
MALT sites is recommended (see references,
No clinical findings favored
a Mikulicz disease or Sjgren's syndrome. Sections disclose chronic parotidis
and myoepithelial sialadenitis in the surrounding parotid tissue. No helicobacter
was found in the ducts or acini.