Clickez sur l'image pour agrandir, ou sur les textes en gras pour visionner les imges ou les pages liés . Pour revenir à l'Observation, pressez Précédente dans votre navigateur

Click on the picture to Zoom or highlighted text to view the linked pictures or pages, . And Back on your browser to review the Observation

School of Myology - Workshop - Class 2002

Case No. 11

Clinical Setting

Female child 5 yo. Neonatal hypotonia. Delayed motor milestones. Thin musculature.

Pathology

Microscopy

  

Cryostat sections demonstrate subsarcolemmal clustering of an eosinophilic material.

 

  

In the trichrome-stained sections they appear red,

 

  

High-power view, they are granular, with rod-like features.

 

 

  

These rod bodies are not detailed by oxidative, nor by ATPase techniques.

 

 

Proposed diagnosis

Congenital myopathy, nemaline (or rod body m.)

 

Back to Workshop Index  -  Next Case