School of Myology - Workshop - Class
Case No. 9
Male infant, 6 months old. Severe hypotonia.
HE shows slight variation in
size of the fibers with no dystrophic changes
Gomori stain display increased
subsarcolemmal and intermyofibrillar membranous material (ragged
Several ragged red fibers show
subsarcolemmal reactivity for NADH deshydrogenase.
Sections react similarly to succinate
Metabolic myopathy (Mitochondrial)