Lymphoid infiltrate of intermediate size with pale cytoplasm and an irregular nucleus. The resemblance of these cells to the centrocyte of the follicle centre has led to the term ‘centrocyte-like' cell.
Lympho-epithelial lesions typical for MALT lymphoma are defined as infiltration of the glandular epithelium by clusters of neoplastic lymphoid cells with associated destruction of gland architecture
The distinction between florid gastritis and low-grade MALT lymphoma may be difficult. In such cases it is essential to
have sufficient biopsy material (up to eight biopsies from endoscopically suspicious areas)..see ref. below.