M 30 ans, douleur abdominale, et trouble du transit.
Polype pdicul du sigmoide, trs large base d'implantation
Le prlvement polypoide est centr par une
densification sous-muqueuse, osinophile,
d'allure fibrillaire, associe
une ectasie vasculaire.
Ce matriel se dpose dans les espaces
privasculaires, dborde sur la musculaire-muqueuse,
et le chorion de la muqueuse. A ce
niveau il existe galement une ectasie
vasculaire superficielle, associe.
La coloration des fibres lastiques (Verhoeff) objective
la positivit et la rpartition du dpt.
Elastose avec ectasie vasculaire. (Elastome?)
PUBMED: Colon and elastosis
|1: Ann Pathol
[Colonic elastoma. A pathologic study of 7 cases].
Kharsa G, Molas G, Potet F, Baglin AC, Vaury P, Grossin M.
Services d'Anatomie Pathologique, Hopital Beaujon, Clichy.
The occurrence of elastic tissue abnormalities in the digestive tract
is not common. There are sometimes observed in genetically transmitted
connective tissue diseases in which numerous systemic complications
are associated as in Ehlers-Danlos and in Gronblad-Strandberg syndromes.
We report 7 cases of an unusual lesion localized in the colon in which
abnormally increased amounts of elastic tissue were observed. This elastosis
raises many nosological and diagnostic difficulties. We propose the
term "colonic elastoma" to describe this lesion. The review
of the literature allows to consider several etiopathogenetic possibilities.
|2: Gut 1985 Mar;26(3):258-66
Elastosis in diverticular disease of the sigmoid
Whiteway J, Morson BC.
Diverticular disease of the sigmoid colon is an increasingly common
clinical problem in the ageing population of western industrialised
countries but the mechanism by which the disease develops remains unknown.
The muscular abnormality is the most striking and consistent feature
and this has been studied by light and electron microscopy in 25 surgical
specimens of uncomplicated diverticular disease and in 25 controls.
This is the first ultrastructural study of human colonic muscle to be
published and shows that the muscle cells in diverticular disease are
normal; neither hypertrophy nor hyperplasia is present. There is, however,
an increase in the elastin content of the taeniae coli by greater than
200% compared with controls: elastin is laid down between the muscle
cells and the normal fascicular pattern of the taeniae coli is distorted.
There is no alteration in the elastin content of the circular muscle.
As elastin is laid down in a contracted form, this elastosis may be
responsible for the shortening or 'contracture' of the taeniae which
in turn leads to the characteristic concertina-like corrugation of the
circular muscle. Such a structural change could explain the altered
behaviour of the colon wall in diverticular disease and its failure
to change on treatment with bran
Abrviations (ND : Non Disponible)