D-016855

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Prsentation Clinique

M 30 ans, douleur abdominale, et trouble du transit.

Endoscopie:

Polype pdicul du sigmoide, trs large base d'implantation   

Pathologie:

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Le prlvement polypoide est centr par une densification sous-muqueuse, osinophile, d'allure fibrillaire, associe une ectasie vasculaire.

 

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Ce matriel se dpose dans les espaces privasculaires, dborde sur la musculaire-muqueuse, et le chorion de la muqueuse. A ce niveau il existe galement une ectasie vasculaire superficielle, associe.

  

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La coloration des fibres lastiques (Verhoeff) objective la positivit et la rpartition du dpt.

    

Diagnostic Propos:

Elastose avec ectasie vasculaire. (Elastome?)

 

PUBMED: Colon and elastosis

1: Ann Pathol 1992;12(6):362-6

[Colonic elastoma. A pathologic study of 7 cases].


Kharsa G, Molas G, Potet F, Baglin AC, Vaury P, Grossin M.

Services d'Anatomie Pathologique, Hopital Beaujon, Clichy.

The occurrence of elastic tissue abnormalities in the digestive tract is not common. There are sometimes observed in genetically transmitted connective tissue diseases in which numerous systemic complications are associated as in Ehlers-Danlos and in Gronblad-Strandberg syndromes. We report 7 cases of an unusual lesion localized in the colon in which abnormally increased amounts of elastic tissue were observed. This elastosis raises many nosological and diagnostic difficulties. We propose the term "colonic elastoma" to describe this lesion. The review of the literature allows to consider several etiopathogenetic possibilities.



 
2: Gut 1985 Mar;26(3):258-66

Elastosis in diverticular disease of the sigmoid colon.

Whiteway J, Morson BC.

Diverticular disease of the sigmoid colon is an increasingly common clinical problem in the ageing population of western industrialised countries but the mechanism by which the disease develops remains unknown. The muscular abnormality is the most striking and consistent feature and this has been studied by light and electron microscopy in 25 surgical specimens of uncomplicated diverticular disease and in 25 controls. This is the first ultrastructural study of human colonic muscle to be published and shows that the muscle cells in diverticular disease are normal; neither hypertrophy nor hyperplasia is present. There is, however, an increase in the elastin content of the taeniae coli by greater than 200% compared with controls: elastin is laid down between the muscle cells and the normal fascicular pattern of the taeniae coli is distorted. There is no alteration in the elastin content of the circular muscle. As elastin is laid down in a contracted form, this elastosis may be responsible for the shortening or 'contracture' of the taeniae which in turn leads to the characteristic concertina-like corrugation of the circular muscle. Such a structural change could explain the altered behaviour of the colon wall in diverticular disease and its failure to change on treatment with bran

 

Abrviations (ND : Non Disponible)