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Présentation Clinique


Clinical Setting

F 84 ans Lésion kératosique de la lèvre inférieure

F 84 yo Scaly, burning lesion of the lower lip

Diagnostic Proposé:









Cheilite actinique lichénoide, acantholytique

Proposed Diagnosis:









Actinic cheilitis, lichenoid, acantholytic.



  • Oral lesions (chronic actinic cheilitis) tend to affect the middle of the lower lip and present as burning or painful scaly lesions.
  • Metastases, however, are rare except for those arising on the ear and lip, which are often associated with more aggressive behavior
  • Sometimes actinic keratoses are atrophic and occasionally, due to marked acantholysis, an acantholytic or pseudoglandular pattern results, which may show a marked resemblance to lesions of Darier's disease (acantholytic actinic keratoses).
  • The dermis underlying and adjacent to the keratosis often shows solar elastosis and vascular ectasia. A lymphohistiocytic infiltrate is commonly evident and sometimes this is associated with the features of an interface dermatitis including basal cell liquefactive degeneration and apoptosis (lichenoid actinic keratosis).


For more details go to:

Actinic keratosis

(Ref. Pathology of the skin, PH McKee, 3rd Ed. Elsevier-Mosby)